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Andrés’ journey to peak health and performance wasn’t accidental — it was a full-blown obsession. “I was just absolutely obsessed with fixing myself and doing, I mean, just absolutely whatever it takes,” he recalls. “Whatever it could be that could possibly help me get to the other side of my health, well-being, and cognitive performance.”
It wasn’t until he stumbled upon the concept of neuroplasticity at age 18 that the path became clear. “When I realized that there was science behind changing and upgrading your brain, I became absolutely obsessed,” Andres says.
Since then, he has built Know Your Physio, a company that helps clients discover their genius through science. Their clients range from ambitious students and entrepreneurs to world champion athletes and top CEOs. Using data and evidence, Andrés helps people perform higher, live better, and extend their longevity.
Physiological Intuition
“I think the most important skill is understanding your body’s signals,” Andres explains. Physiological intuition is about tuning into what your body needs — whether that’s movement, rest, or recovery — and combining it with hard metrics to optimize performance.
Core Metrics for Performance
Three numbers stand out:
Circadian Rhythm & Recovery
Andres emphasizes aligning habits with natural rhythms. Tools like FlyKit — which includes supplements, blue-blocking glasses, and a personalized AI app — guide travel, eating, and sleep patterns to minimize jet lag and inflammatory stress from flights.
“Recovery is non-negotiable,” he says. “Even the highest performers need a built-in day of rest. It reinforces all the effort you put in during the week and dramatically improves quality of life.”
“My number one practice for leveling up my game is sprinting. It’s evolutionarily consistent with our survival, and it’s a phenomenal way to increase VO2 max — the most highly correlated metric with longevity.”
High-intensity, primal exercise that boosts cardiovascular health, power, and cognitive alertness.
“Exercising in community pushes you harder and holds you accountable. Dr. Kelly McGonigal calls this the joy of movement — we’re literally designed to move together.”
Group workouts increase motivation, endorphins, and social bonding.
“There’s something primal about having something on the line. Playing it safe will never teach you as much about yourself or others.”
High-stakes challenges cultivate resilience, courage, and focus.
“I discovered this at the Austin Health Optimization Summit. It contains paraxanthine, a metabolite of caffeine. Unlike caffeine, it energizes me without affecting my sleep.”
Sustained, clean energy with a shorter half-life than caffeine — perfect for late-day focus.
“Maybe once a week, if I need a micro boost, I take a very tiny dose of nicotine. Nic Nac Naturals gives me subtle cognitive support without overdoing it.”
Supports alertness and cognitive endurance in controlled doses.
“Even the most high-performing people should have one day a week dedicated to full recovery, mentally and physically. It’s a game changer.”
A mental and physical reset that reinforces weekly efforts.
“For long workdays or multiple podcasts, I use KE4, the world’s strongest exogenous ketone esters. It works for both physical and cognitive endurance, and surprisingly, sleep efficiency too.”
Supports extended mental and physical performance while optimizing metabolism.
“My favorite shoes — they spread the toes naturally, help build my arch, and I wear them every time I exercise. I love these shoes.”
Minimalist footwear promotes natural foot mechanics and posture.
“Daily wear is WYR — cotton shirts and shorts. Simple, breathable, and perfect for movement.”
“When I dress up, I wear Wear Shepherds — custom linen. Linen feels great, is breathable, and avoids polyester, which can impact hormones.”
“I wear RA Optics blue-blocking glasses. Yellow lenses for day, red for night — game-changing for circadian rhythm and eye health.”
“Brick literally blocks your phone. I used to mock it, but now I realize how much time we waste — it could save decades over a lifetime.”
A physical and digital habit-shaping tool that protects focus and mental bandwidth.
Andres’ approach isn’t just about raw data or supplements. It’s about blending science, intuition, and lifestyle into a high-performance system that’s sustainable. From sprinting to circadian optimization, his Flow Stack is a blueprint for anyone looking to maximize energy, health, and mental clarity.
“If you tune into your body, challenge yourself, and use science to guide your decisions, you can upgrade not just your health, but your entire life,” Andrés Preschel
